Avana 200 mg Avanafil is a medication primarily prescribed for the treatment of erectile dysfunction (ED) in men. Avanafil, the active ingredient in Avana 200 mg, belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. These medications work by increasing blood flow to the penis during sexual stimulation, thus helping men achieve and maintain an erection sufficient for sexual activity.