San Francisco, 03 May 2024: The Report Gene Synthesis Market Size, Share & Trends Analysis Report By Method (Solid-phase Synthesis, Chip-based Synthesis, PCR-based Enzyme Synthesis), By Service, By Application, By End-use, By Region, And Segment Forecasts, 2023 - 2030

The global gene synthesis market size is expected to reach USD 5.78 billion by 2030, registering a CAGR of 16.1% from 2023 to 2030 according to a new report by Grand View Research, Inc. Development of the market is due  to the growing investment in the synthetic biology field, favorable government regulations, and technological advancements in the gene synthesis market. In January 2022, synthetic DNA manufacturer Twist Bioscience announced plans of developing EDS technology at the J.P. Morgan Health Care Conference. The company established an enzymatic DNA synthesis technology that is novel, low-cost, scarless, and scalable.

The introduction of novel DNA synthesis platforms with technologically advanced specifications that address the increased demand of researchers is also contributing to the overall growth. For instance, in June 2021, DNA Script introduced the SYNTAX System, which is the nucleic acid printer based on EDS technology. Similarly, in December 2020, Evonetix Ltd. entered into a research collaboration with Analog Devices, Inc. Under the terms of the agreement, the companies collaborated on Evonetix's Microelectromechanical System-based silicon chips' improvement and commercial scale-up, as well as the development of a DNA desktop writer.

Researchers, as well as biotechnology and pharmaceutical corporations, have become increasingly interested in targeted therapy during recent years. It has become a popular method of disease management. In the near future, targeted therapy in conjunction with chemotherapy and immunotherapy is likely to develop significantly, presenting lucrative prospects for both emerging & established competitors in the gene synthesis market.

Key players are focusing on product development and are entering into partnerships and collaborations to expand their product offerings. For instance, In January 2022, Thermo Fisher Scientific, Inc. completed the acquisition of PeproTech, Inc.- a producer of antibodies and vectors. This acquisition may help the company strengthen its position in the market. Similarly, in July 2021, GenScript hosted the GenScript Gene & Cell Engineering Virtual Summit. This event focused on highlighting synthetic biology research to enhance protein design, drug discovery, and genome editing, enabling the company to increase its customer base.

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The growth of the market is attributed to factors such as favorable government policies relating to synthetic biology. Investors have been more focused on synthetic biology research during the past few years. Approximately USD 8.0 billion in governmental and commercial funding was allocated to the synthetic biology sector in 2020. The COVID-19 outbreak has benefited the gene synthesis market by creating significant growth opportunities. Researchers are exploring untapped possibilities in the gene synthesis field, which is helping to boost market growth in terms of revenue generation. For instance, researchers at the National Institute of Standards and Technology have developed synthetic SARS-CoV-2 gene fragments to assist researchers to develop accurate and reliable diagnostic tests for the disease.

Gene Synthesis Market Report Highlights

• The growth is attributed to the growing demand for the synthetic biology, coupled with increasing government support to offer funds for R&D initiatives in synthetic biology
• By method, solid-phase synthesis dominated in 2022 as it offers high accuracy and is a prominent technology for the applications in several fields and for various research purposes
• By services, antibody DNA synthesis dominated the gene synthesis market in 2022, owing to the presence of significant players such as Synbio offers services, Twist Bioscience Corporation, and others, offering services in this segment
• By application, the gene & cell therapy development segment dominated the gene synthesis market in 2022. This is attributed to the growing number of R&D programs for the development of cell and gene therapies
• By end-use, academic and government research institute dominated the gene synthesis market in 2022, as most of the gene synthesis process is performed in the research settings for clinical research and investigational programs
• North America captured the highest share in 2022 owing to the well-established molecular biology infrastructure along with the presence of a significant number of market players in the region

Synthetic DNA technological advancements are getting significant traction as a viable method to address concerns associated with the increasing number of emerging viruses and the potential threats of the next global pandemic. The SARS-CoV-2 pandemic along with pandemics involving other novel diseases in the near future can be rapidly addressed with the help of this promising technique to quickly replicate and analyze genes of interest.

Targeted therapy has gained significant interest from the biotechnology and pharmaceutical industry and researchers. It has become an important technique of disease management. Targeted therapy in combination with immunotherapy and chemotherapy is anticipated to witness significant growth in the coming years. This would open up lucrative opportunities for both established and emerging players in the gene synthesis market.

The lack of skilled professionals in the field of gene synthesis and biotechnology is one of the main factors which could hinder the market growth, as the companies operating in this market would require trained and experienced staff at their facilities. Therefore, companies are entering into several strategic collaborations with universities to offer staff online workshops, on-site training, and sponsored projects to develop the right professionals. This would further help to drive the gene synthesis market growth.

Gene Synthesis Market Report Scope

Key players operating in the market are taking several strategic initiatives such as entering into collaborations, partnerships, and geographical expansions in favorable regions. Companies are introducing novel products to strengthen their product portfolio in the market. For instance, in March 2022, ProteoGenix launched XtenCHO Transient CHO Expression System.

List of Key Players of Gene Synthesis Market

• GenScript
• Brooks Automation, Inc. (GENEWIZ)
• Boster Biological Technology
• Twist Bioscience
• ProteoGenix, Inc
• Biomatik
• ProMab Biotechnologies, Inc.
• Thermo Fisher Scientific, Inc.
• Integrated DNA Technologies, Inc.
• OriGene Technologies, Inc.