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It is particularly relevant for those aiming to preserve fertility as it has demonstrated efficacy in restoring the HPG axis by promoting the production and secretion of LH and FSH, thus enhancing physiological testosterone levels (6

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Treatment of these men with an anti-oestrogen or an aromatase inhibitor can increase gonadotropin and testosterone levels; however, enclomiphene citrate is not proposed for some forms of secondary hypogonadism such as pituitary tumours, craniopharingiomas, haemochromatsis or congenital GnRH deficienc

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