Abiraterone Acetate 250 mg, sold under the brand name Zytiga, is an oral medication used primarily for the treatment of prostate cancer. It functions by inhibiting the production of androgens (male hormones) in the body, which can promote the growth of prostate cancer cells. Indications: Abiraterone is approved for use in combination with prednisone for the treatment of: Metastatic Castration-Resistant Prostate Cancer (mCRPC): This is prostate cancer that continues to progress despite low levels of testosterone achieved through surgical or medical castration. Metastatic High-Risk Castration-Sensitive Prostate Cancer (mCSPC): This refers to prostate cancer that has spread to other parts of the body and still responds to treatments that lower testosterone levels. Administration: Dosage: Typically, the dosage is 1,000 mg (four 250 mg tablets) taken once daily in combination with 5 mg of prednisone taken twice daily. With Food: Abiraterone should be taken on an empty stomach, as food can significantly increase the absorption of the drug, potentially leading to higher than intended concentrations in the blood. Side Effects: Common side effects include: Hypertension (High Blood Pressure) Hypokalemia (Low Potassium Levels) Edema (Fluid Retention) Fatigue Liver Enzyme Abnormalities Less common but serious side effects may include heart issues, such as heart failure, particularly in patients with pre-existing cardiovascular conditions.Does Abiraterone Price cause muscle loss? Abiraterone and enzalutamide are associated with losses in muscle mass compared with luteinizing hormone-releasing hormone agonists. These treatments impact subcutaneous and visceral fat mass, suggesting distinct roles of androgens in these tissues.
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